Very low field F-19 MRI of perfluoro-octylbromide: minimizing chemical shift effects and signal loss due to scalar coupling

Author(s):
Parsa, J. (0000-0002-0845-8492); O'Reilly, T.; Webb, A.
Published
2021
Publication type
Article / Letter to editor

Abstract

F-19 images have been obtained from perflurooctylbromide (PFOB) at very low magnetic field (50 mT). The small spectral dispersion (in Hz) means that all fluorine nuclei contribute to the signal without chemical shift artifacts or the need for specialized imaging sequences. Turbo spin echo trains with short interpulse intervals and full 180 degrees refocussing pulses suppress scalar coupling, leading to long apparent T-2 values and highly efficient data collection. Overall, the detection efficiency of PFOB is very similar that of water in tissue. (C) 2021 The Author(s). Published by Elsevier Inc.

Low fieldFluorine MRITurbo-spin echoScalar coupling
Date issued
2021-04-01
Language
English
Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
Is part of
Journal of Magnetic Resonance
hdl
1887/3277691
doi
10.1016/j.jmr.2021.106946
URL
https://www.sciencedirect.com/science/article/pii/S1090780721000355?via%3Dihub