Bidirectional effects of IL-10+ regulatory B cells in Ldlr−/− mice

Author(s):
Douna, H. (0000-0003-4686-8393); Amersfoort, J. (0000-0002-3083-4642); Schaftenaar, F.H. (0000-0001-5742-489x); Kroon, S.; Puijvelde, G.H.M. van (0000-0001-8673-8521); Kuiper, J.; Foks, A.C. (0000-0002-9747-3458)
Published
2018
Publication type
Article / Letter to editor

Abstract

Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response through interleukin-10 (IL-10). Current data regarding Bregs and atherosclerosis is scarce and conflicting.

B cells on atherosclerosis.

B cells on atherosclerosis.

B cells in atherosclerosis.

Cardiovascular diseaseAtherosclerosisB cellsInterleukin-10Regulatory B cellsLdlr −/- miceWestern type diet
Date issued
2018-11-09
Language
English
Is part of
hdl
1887/3203197
doi
10.1016/j.atherosclerosis.2018.11.019