Linking Smokers' Susceptibility to Tuberculosis with Lysosomal Storage Disorders.

Author(s):
Meijer, A.H. (0000-0002-1325-0725); Aerts, J.M.F.G. (0000-0001-8168-2565)
Published
2016
Publication type
Article / Letter to editor

Abstract

Reporting in Cell, Berg et al. (2016) reveal a connection between genetic lysosomal storage disorders and the ability of macrophages to migrate and control mycobacterial infection. This insight, resulting from a zebrafish genetic screen, inspired the authors to propose an explanation for the increased susceptibility of cigarette smokers to tuberculosis.

Date issued
2016-04-18
Language
English
Is part of
hdl
1887/3199849
doi
10.1016/j.devcel.2016.04.004