Leiden University Scholarly Publications

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Peterse, E. (2021)

Synthesis of cyclic peptides as bioconjugation platforms

Doctoral Thesis
Cyclic peptides are investigated as a platform to induce different orientations between various ligands. Through click chemistry, a variety of Toll-like receptor ligands can be attached to the cyclic peptides, which are based on gramicidin S.
Gramicidin S
Click Chemistry
Toll-like receptor ligands
Cyclic Peptide
On-resin cyclization
All authors
Peterse, E.
Supervisor
Overkleeft, H.S.
Co-supervisor
Filippov, D.V.
Committee
Marel, G.A. van der; Stelt, M. van der; Ossendorp, F.A.; Maarseveen, J. van; Kasteren, S.I. van; Boyle, A.L.
Qualification
Doctor (dr.)
Awarding Institution
Leiden Institute of Chemistry (LIC), Faculty of Science, Leiden University
Date
2021-06-29
ISBN (print)
9789463327596