COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology - COMPLOT

Abstract

Plasma microcontact patterning (P mu CP) and replica molding were combined to make PDMS/glass microfluidic devices with beta-cyclodextrin (beta-CD) patterns attached covalently on the glass surface inside microchannels. The supramolecular reactivity, reusability and association constant of beta-CD with Cy5-Ad2 was tested by analyzing signal-to-noise ratios of patterns vs. spacing with fluorescence microscopy.