The role of autophagy during carbon starvation in Aspergillus niger

Author(s):
Burggraaf, M.A.
Published
2021
Publication type
Doctoral Thesis

Abstract

Autopaghy is an intracellular degradation system which targets cytosolic components to lytic compartments for degradation and recycling of the building blocks of the cell. The process is highly induced by carbon starvation conditions. In this thesis, different roles of autophagy in the filamentous fungus Aspergillus niger were studied, focusing on its role during carbon starvation, endoplasmic reticulum (ER) stress and unconventional protein secretion.

Aspergillus nigerAutophagyCarbon starvationTranscriptomeER-associated degradation (ERAD)Unconventional protein secretion (UPS)
Defense date
2021-05-25
Language
English
Supervisor(s)
Ram, A.F.J.; Punt, P.J.; Hondel, C.A.M.J.J. van den
Committee member(s)
Wezel, G.P. van; Winde, J.H. de; Kleij, I.J. van der; Meijer, A.H.; Pócsi, I.; Wösten, H.A.B.
Qualification
Ph.D.
Degree granting institution
Institute of Biology Leiden (IBL), Faculty of Science, Leiden University, Leiden
hdl
1887/3179455
ISBN(s)
9789464232394