Diphtheria toxoid dissolving microneedle vaccination: Adjuvant screening and effect of repeated-fractional dose administration

Author(s):
Leone, M.L.; Romeijn, S.G.; Du, G.; Dévédec, S.E. Le; Vrieling, H.; O'Mahony, C.; Bouwstra, J.A. (0000-0002-7123-6868); Kersten, G.F.A.
Published
2020
Publication type
Article / Letter to editor

Abstract

in a 15 times higher dose of DT, as well as subcutaneous injected DT-poly(I:C) in a similar DT dose. Summarizing, adjuvant-free dMNs showed to be a promising delivery tool for vaccination performed in SFD administration.

Date issued
2020-04-30
Language
English
Is part of
International Journal of Pharmaceutics (2020), Vol. 580, p. 119182
hdl
1887/3176514
doi
10.1016/j.ijpharm.2020.119182