Peptide Amphiphiles and their use in Supramolecular Chemistry

Author(s):
Versluis, F.
Published
2013
Publication type
Doctoral Thesis

Abstract

In this thesis the behavior and functionality of peptide amphiphiles at the surface of bilayer vesicles is examined. By controlling the behavior of the surface bound peptides, I was able to construct assemblies which could: 1) release their content (triggered by pH), 2) fuse in a targeted and controlled manner or 3) dock to cells and zebrafish embryos

Supramolecular chemistryPeptide chemistryChemical biologyMembrane fusion
Defense date
2013-12-09
Language
English
Supervisor(s)
Fraaije, J.G.E.M.
Advisor(s)
Kros, A.
Committee member(s)
Otto, S.; Huskens, J.; Ashkenasy, G.
Qualification
Ph.D.
Degree granting institution
Leiden Institute of Chemistry, Faculty of Science, Leiden University, Leiden
hdl
1887/22801