Human identification & forensic analyses of degraded or low level DNA
Abstract
DNA-based human identification is employed in varying situations, such as disaster victim identification, relationship testing and forensic analyses. When DNA is of low quality and/or quantity, standard methods for DNA profiling may not suffice. The research described in this thesis is aimed at the development of additional or alternative methods to extract information from a person__s DNA. The explored methods include: optimised sampling, the use of smaller and/or other types of DNA markers, increased analysis sensitivity, DNA repair, and combining marker sets. These studies have been performed to get closer to the answer regarding the question: __To whom belongs this body?__
Single nucleotide polymorphism (SNP)Short tandem repeat (STR)Molecular biologyLow template (LT) DNAHuman identificationForensic scienceForensic geneticsDisaster victim identification (DVI)Degraded DNADNA repair enzyme
