On real-world patients and real-world outcomes : the Leiden Routine Outcome Monitoring Study in patients with mood, anxiety and somatoform disorders

Noorden, M.S. van (2012)

Doctoral Thesis

This thesis focuses on real-world patients and real-world outcomes by using Routine Outcome Monitoring (ROM) in patients with Mood, Anxiety, and Somatoform (MAS) disorders. The primary aims of the series of studies were to investigate correlates of disease characteristics in a large cohort of treatment-seeking patients with MAS disorders, and to discuss these findings in relation to existing data derived from RCTs and general population studies. In addition, using prospective data, we investigated whether baseline characteristics measured with ROM could predict outcomes in real-world or naturalistic treatment settings. The secondary aim was to assess the feasibility of conducting large-scale clinical epidemiological research with ROM data that had been collected in everyday clinical practice, thereby representing the phenotype of __real__ patients.

• Somatoform disorders
• Anxiety disorders
• Mood disorders
• Routine Outcome Monitoring

• All authors: Noorden, M.S. van
• Supervisor: Zitman, F.G.
• Co-supervisor: Giltay, E.J.; Wee, N.J.A. van der
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden University Medical Center (LUMC), Leiden University
• Date: 2012-10-11