Metabolomics of biofluids : from analytical tools to data interpretation

Author(s):
Nevedomskaya, E.
Published
2011
Publication type
Doctoral Thesis

Abstract

The chapters that comprised this thesis cover a broad range of subjects from analytical method development to clinical application of metabolic profiling. They are united by the facts that all of these studies aimed at analysis of biological fluids and that the presented methods and approaches may ultimately become parts of a robust metabolomics workflow that might be used in a future personalized medicine.

Nuclear magnetic resonance spectroscopyMultivariate data analysisMetabolic profilingMass spectrometryLiquid chromatographyData pre-processingCapillary electrophoresis
Defense date
2011-11-23
Language
English
Supervisor(s)
Deelder, A.M.
Advisor(s)
Mayboroda, O.A.
Qualification
Ph.D.
Degree granting institution
Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/18135
ISBN(s)
9789461820389

Funding

Sponsorship
Bruker BioSpin GmbH, Germany; Dionex Benelux B.V.; Beckman Coulter (Nederland) B.V.; Bruker Nederland B.V.