Integrin signaling modes controlling cell migration and metastasis

Truong, H.H. (2011)

Doctoral Thesis

The aim of this thesis is to address how integrin-mediated signaling regulates cellular processes that have profound effects on cell morphology, motility, cancer metastasis, and FN fibrillogenesis, and how these findings can be utilized for relevant medical purposes or advancement of drug discovery.

• Metastasis
• Integrins
• EMT
• Drug target
• Cohesion migration
• Cell adhesion
• Cancer

• All authors: Truong, H.H.
• Supervisor: Water, B. van de
• Co-supervisor: Danen, E.H.J.
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden University Medical Center (LUMC), Leiden University
• Date: 2011-10-27
• ISBN (print): 9789085704225
• Sponsorship: LACDR and KWF