Integrin signaling modes controlling cell migration and metastasis

Author(s):
Truong, H.H.
Published
2011
Publication type
Doctoral Thesis

Abstract

The aim of this thesis is to address how integrin-mediated signaling regulates cellular processes that have profound effects on cell morphology, motility, cancer metastasis, and FN fibrillogenesis, and how these findings can be utilized for relevant medical purposes or advancement of drug discovery.

MetastasisIntegrinsEMTDrug targetCohesion migrationCell adhesionCancer
Defense date
2011-10-27
Language
English
Supervisor(s)
Water, B. van de
Advisor(s)
Danen, E.H.J.
Qualification
Ph.D.
Degree granting institution
Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/17990
ISBN(s)
9789085704225

Funding

Sponsorship
LACDR and KWF