Predictive factors for outcome of rheumatoid arthritis

Author(s):
Linden, M.P.M. van der
Published
2011
Publication type
Doctoral Thesis

Abstract

RA is a chronic and progressive autoimmune disease affecting approximately 1% of the population worldwide, and has a large risk for causing disability of patients and consequently high costs in health care if left un- or improperly treated. To prevent this, patients with RA need to be identified as early as possible and treated adequately to prevent worse outcome. Early recognition, together with prediction of the disease outcome at the individual patient level would allow to achieve personalized medicine. The main scope of this thesis was to identify and evaluate the quality of risk factors for their usefulness in predicting disease course and outcome of RA. To this end, characteristics and disease outcome of RA patients included in the Leiden EAC were studied.

Risk predictionRheumatoid arthritisJoint damage
Defense date
2011-09-15
Language
English
Supervisor(s)
Huizinga, T.W.J.
Advisor(s)
Helm-van Mil, A.H.M. van der
Qualification
Ph.D.
Degree granting institution
Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/17836
ISBN(s)
9789461691071

Funding

Sponsorship
Abbott BV, Dutch Arthritis Association (Reumafonds), J.E. Jurriaanse Stichting, Merck Sharp & Dohme BV, Pfizer BV, Roche Nederland BV, Teva Nederland BV