Human oesophagostomiasis: clinical presentations and subclinical colonic pathology

Abstract

In 1986, following the discovery that Oesophagostomum eggs are excreted by people living in northern Ghana and Togo, Polderman and Gigase concluded that Oesophagostomum worms are able to complete their life cycle in humans, and that the helminth causes considerable disease in this area. There have been many cases of clinical oesophagostomiasis reported in the literature over the last century, but diagnosis has usually been based on a pathology specimen and clinical details have been sparse. We therefore amassed a cohort of 156 patients presenting to Nalerigu hospital in northern Ghana, and identified two distinct clinical presentations of the disease, Dapaong tumour and multinodular disease.