The zoonotic potential of Oesophagostomum bifurcum in Ghana. Epidemiological, morphological and genetic studies

Gruijter, J.M. de (2005)

Doctoral Thesis

The overall objective of the present study was to assess the zoonotic potential of O. bifurcum, in other words to assess the risk of transmission of the simian parasite to humans. Knowledge of the zoonotic potential of O. bifurcum is central to controlling the infection in humans. The specific research aims were (1) to establish the presence of O. bifurcum in different species of non-human primates in two geographical areas outside of the endemic region in Ghana, (2) to determine whether there is any significant morphological variation between O. bifurcum from human and from different species of non-human primates, (3) to test the hypothesis that O. bifurcum from humans is genetically distinct from the parasite from nonhuman primates, and (4) to establish whether the hookworm Ancylostoma duodenale occurs in sympatry with O. bifurcum and impacts on human health in northern Ghana.

• Oesophagostomum bifurcum
• Zoo_nosen
• Togo
• Ghana

• All authors: Gruijter, J.M. de
• Supervisor: Deelder, A.M.
• Co-supervisor: Polderman, A.M.
• Qualification: Doctor (dr.)
• Awarding Institution: Leiden University Medical Center (LUMC), Leiden University
• Date: 2005-06-01