Cluster headache: Clinical aspects and therapy with neurostimulation

Abstract

This thesis provides an insight in the clinical aspects and therapy with neurostimulation in cluster headache patients. An unique cohort of Dutch cluster headache patients (LUCA - Leiden University Cluster headache neuro-Analysis programme) has been used to analyse different clinical aspects like drug-use, chronobiology and aura symptoms in cluster headache patients. Regarding neuromodulation: a case-report about occipital nerve stimulation and pregnancy is described here and a meta-analysis of non-invasive vagal nerve stimulation as acute treatment in both episodic and chronic cluster headache.

Cluster headacheNeuromodulationHeadacheTrigeminal autonomic cephalalgiaVagal nerve stimulationAuraDrug useChronobiologyOccipital nerve stimulationCluster-tic-syndrome