Anti-glycan antibody responses during infection with Schistosoma: Searching for the sweet spots

Author(s):
Yang, Y.-Y.M.
Published
2020
Publication type
Doctoral Thesis

Abstract

During a schistosome infection, the host generates a plethora of antibodies against schistosome glycans. This thesis looks into the anti-schistosome-glycan antibody dynamics in different hosts with the aim of identifying targets that are relevant in the context of infection and protection.

Anti-glycan antibody responsesSchistosomiasisGlycoconjugateRA cercariae vaccinationNon-human primate modelsGlycan microarrayGlycan vaccinesSchistosome
Defense date
2020-08-26
Language
English
Supervisor(s)
Hokke, C.H.
Advisor(s)
Diepen, A. van
Committee member(s)
Wuhrer, M.; Geluk, A.; Toes, R.E.M.; Geldhof, P.; Sorge, N.M. van
Qualification
Ph.D.
Degree granting institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University, Leiden
hdl
1887/135954
ISBN(s)
9789464160635