Leiden University Scholarly Publications

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Pieterse, Q.D. (2007)

Early stage cervical cancer : quality of cancer care and quality of life

Doctoral Thesis
To improve quality of cancer care treatment-related information is needed. This could be acquired by registries. Since January 1984, the Leiden University Medical Center (LUMC) collects prospectively more than 200 relevant clinical and pathological parameters of women with cervical cancer treated in the LUMC. The purpose of this thesis was to use the treatment-related information of this database, to get inside information and to become aware of possibilities for improvement in the current treatment procedures, in order to monitor the quality of treatment. Furthermore, when results of cancer treatment in terms of survival are good it is also important to focus on the sequelae of the treatment. The incidence of lymphedema, urinary and colorectal dysfunction has been reported with variable rates and sexual dysfunction after radical hysterectomy has been shown to occur in about 25% of the patients. Furthermore, a study assessed by vaginal plethysmography, showed that radical...Show moreTo improve quality of cancer care treatment-related information is needed. This could be acquired by registries. Since January 1984, the Leiden University Medical Center (LUMC) collects prospectively more than 200 relevant clinical and pathological parameters of women with cervical cancer treated in the LUMC. The purpose of this thesis was to use the treatment-related information of this database, to get inside information and to become aware of possibilities for improvement in the current treatment procedures, in order to monitor the quality of treatment. Furthermore, when results of cancer treatment in terms of survival are good it is also important to focus on the sequelae of the treatment. The incidence of lymphedema, urinary and colorectal dysfunction has been reported with variable rates and sexual dysfunction after radical hysterectomy has been shown to occur in about 25% of the patients. Furthermore, a study assessed by vaginal plethysmography, showed that radical hysterectomy seems to be associated with a disturbed vaginal blood flow response during sexual arousal. The second purpose of this thesis was to monitor the sequelae of the treatment of women with a history of early stage cervical cancer in order to have measures in attempts to improve the quality of life.Show less
Cervical cancer
Multi-state
Nerve-sparing
Photoplethysmography
Quality of life
Questionnaire
Radical hysterectomy
Risk factors
Sexual function
Survival
All authors
Pieterse, Q.D.
Supervisor
Kenter, G.G.; Trimbos, J.B.M.Z.
Co-supervisor
Kuile, M.M. ter
Qualification
Doctor (dr.)
Awarding Institution
Leiden University Medical Center (LUMC), Leiden University
Date
2007-09-13
ISBN (print)
9789085593003

Juridical information

Court
LEI Universiteit Leiden

Funding

Sponsorship
Ortho-Biotec, division of Janssen-Cilaq BV. Medical Dynamics Smiths medical Nederland BV Amgen BV Sanofi Pasteur MSD N.V. J.E.Jurriaanse Stichting Stichting Nationaal Fonds tegen Kanker Nycomed Nederland B.V.