Characterization and prediction of positional 4-hydroxyproline and sulfotyrosine, two post-translational modifications that can occur at substantial levels in CHO cells-expressed biotherapeutics

Author(s):
Tyshchuk, O.; Gstottner, C.; Funk, D.; Nicolardi, S.; Frost, S.; Klostermann, S.; Becke, T.; Jolkver, E.; Schumacher, F.; Koller, C.F.; Volger, H.R.; Wuhrer, M. (0000-0002-0814-4995); Bulau, P.; Molhoj, I.
Published
2019
Publication type
Article / Letter to editor
Biotherapeuticsfab purificationMALDI-ISD FT-ICRhydroxyprolinemass spectrometryPTMpost-translational modificationsulfotyrosine
Date issued
2019-10-03
Language
English
Is part of
mAbs (2019), Vol. 11, no. 7, p. 1219-1232
hdl
1887/120352
doi
10.1080/19420862.2019.1635865