Complement-dependent cytotoxicity induced by therapeutic antibodies in B-cell acute lymphoblastic leukemia is dictated by target antigen expression levels and augmented by loss of membrane-bound complement inhibitors

Author(s):
Loeff, F.C.; Egmond, H.M.E. van; Nijmeijer, B.A.; Falkenburg, J.H.F.; Halkes, C.J.; Jedema, I.
Published
2017
Publication type
Article / Letter to editor
Complement-dependent cytotoxicityB-cell acute lymphoblastic leukemiamembrane-bound complement regulatory proteinsantibody therapyCD55CD59
Date issued
2017-12-31
Language
English
Is part of
Leukemia & Lymphoma (2017), Vol. 58, no. 9, p. 2185-2195
hdl
1887/115706
doi
10.1080/10428194.2017.1281411