Parvovirus B19 infection in pregnancy: new insights and management

Author(s):
Jong, E.P. de; Walther, F.J.; Kroes, A.C.M.; Oepkes, D.
Published
2011
Publication type
Article / Letter to editor

Abstract

In this article, we review the virology, pathology, epidemiology and clinical spectrum of intrauterine human parvovirus B19 (B19V) infection, including intrauterine fetal death, non-immune hydrops fetalis, thrombocytopenia and neurological manifestations such as pediatric stroke and perivascular calcifications. In addition, we discuss the new insights into the neurodevelopmental outcome of intrauterine B19V infection. Current diagnosis and management of B19V infection is summarized, including a diagnostic and follow-up flowchart for practical clinical use. Copyright (C) 2011 John Wiley & Sons, Ltd.

parvovirus B19 fetal infection hydrops fetalis intrauterine blood transfusion management intrauterine fetal-death maternal infection cellular coreceptor hydrops-fetalis viral load risk diagnosis anemia stroke thrombocytopenia
Date issued
2011-05-31
Language
English
Is part of
Prenatal Diagnosis (2011), Vol. 31, no. 5, p. 419-425
hdl
1887/109059
doi
10.1002/pd.2714