The Burden of Cure: Long-term Side Effects Following Hematopoietic Stem Cell Transplantation (HSCT) in Children

Author(s):
Baker, K.S.; Bresters, D.; Sande, J.E.
Published
2010
Publication type
Article / Letter to editor

Abstract

Children who survive hematopoietic stem cell transplantation (HSCT) are at risk for an inordinate number of long-term side effects. Late effects can be secondary to the underlying diagnosis for which the transplant is performed, prior treatment of the disease, the transplant preparative regimen, treatment of the complications of transplant, and immunologic interactions between the graft and the host. This article describes the risks and manifestations of the most commonly reported late effects in survivors of pediatric HSCT.

Late effects Pediatric bone marrow transplantation Long-term follow-up bone-marrow-transplantation quality-of-life total-body irradiation cord blood transplantation childhood-cancer survivor focal nodular hyperplasia effects working party versus-host-disease high-dose busulfan immune reconstitution
Date issued
2010-02-28
Language
English
Is part of
Pediatric Clinics of North America (2010), Vol. 57, no. 1, p. 323
hdl
1887/109056
doi
10.1016/j.pcl.2009.11.008