Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression

Author(s):
Bailey-Elkin, B.A.; Knaap, R.C.M.; Johnson, G.G.; Dalebout, T.J.; Ninaber, D.K.; Kasteren, P.B. van; Bredenbeek, P.J.; Snijder, E.J. (0000-0003-3297-2309); Kikkert, M. (0000-0002-5779-7386); Mark, B.L.
Published
2014
Publication type
Article / Letter to editor
Cysteine ProteaseDeubiquitylation (Deubiquitination)Innate ImmunityStructural BiologyViral ImmunologyX-ray CrystallographyMiddle East Respiratory Syndrome CoronavirusPLpro
Date issued
2014-12-12
Language
English
Is part of
Journal of Biological Chemistry (2014), Vol. 289, no. 50, p. 34667-34682
hdl
1887/105649
doi
10.1074/jbc.M114.609644