Stressed-out stress systems: dysregulated stress-systems in the pathophysiology of stress-related disorders

Abstract

This thesis aims to further unravel the role of the stress-systems in the pathophysiology of stress-related psychiatric disorders, by exploring elements of regulation and dysregulation of the two major stress systems (i.e. the ANS and the HPA-axis), and their relation with psychological and psychiatric characteristics.

HPA-axissympathetic nervous system (SNS)CortisolAlpha-amylaseCushing's disease(f)MRI